Rationally designed viruses for use as vaccines or solid tumor therapies

Codagenix is a clinical stage synthetic biology company that uses software to recode the genomes of viruses, constructing live-attenuated vaccines or viruses to prevent viral infections or treat solid tumors. Codagenix’s recoded vaccine candidates are a perfect antigenic match to the target virus and induce a robust immune response to all viral antigens. For cancer, our nimble platform allows us to turn a virus into a potential oncolytic immuno-oncology therapies. Both programs rely on scalable, low-cost manufacturing.

Safe and effective live-attenuated vaccines, presenting all target antigens

Target customized oncolytics to treat primary tumors and shrink off-site metastases


RSV hospitalizations among adults 65+ no vaccine

48.8 million

Flu cases in 2017-18, current vaccines <37% effective

1 in 8

US women (about 12%) will develop invasive breast cancer during lifetime.

Our breakthrough approach to live-attenuated virus design

1. Recode

2. Synthesize

3. Transfect

4. Recover

  • December 02, 2019

    Codagenix and USDA-ARS Renew CRADA for Continued Development of Synthetic, Multivalent Foot-and-Mouth Disease Virus (FMDV) Vaccine

    Farmingdale, New York, December 2, 2019– Codagenix, Inc., announces today the renewal of a cooperative research and development agreement (CRADA) with the USDA Agricultural Research Service’s (ARS) Foreign Animal Disease Research Unit,  located at the Plum Island Animal Disease Center (PIADC) on Plum Island.

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  • September 27, 2019

    Codagenix presenting at ID Week

    Come find Codagenix at ID Week, Oct 2-6 in Washington, DC. We are presenting two posters On Oct 5, describing our RSV and tetravalent Dengue vaccines: Poster #2764 : Generation of a Balanced, Tetravalent Dengue Vaccine Based on Contemporary Strains Using a Computational, Synthetic Biology-based Platform Poster #2777 : Synthetic Live-Attenuated Vaccine Against RSV is […]

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